Worldwide around 50 million people live with dementia, and this number is projected to increase to 152 million by 2050, rising particularly in low and middle-income countries.

An update to the 2017 Lancet Commission on dementia, prevention, intervention and care expands the number of modifiable risk factors from 9 to 12, to now include head injuries in mid-life, excessive alcohol consumption in mid-life, and exposure to air pollution in later life.

Forty per cent of dementia cases could be prevented or delayed by targeting these 12 modifiable risk factors. The 2020 Commission update calls for nations and individuals to be ambitious about preventing dementia, and lays out a set of policies and lifestyle changes to help

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